Overview
Surfaces coated with peptides provide customizable platforms for capturing biomolecules based on sequence-specific or motif-driven interactions. By immobilizing selected peptides on laboratory substrates, researchers create surfaces with defined binding characteristics, enabling selective capture and enrichment of target species. This approach can be applied to microplates, sensor surfaces, or other experimental supports.
Peptide-coated surfaces are engineered to present binding sites in a stable, accessible configuration. Through careful selection of sequences and immobilization methods, these surfaces can be tuned for affinity, selectivity, and robustness under experimental conditions.
Research Uses
- Affinity-based capture surfaces – Surfaces decorated with recognition sequences capture molecules that display complementary features.
- Surface-peptide conjugation – Chemical strategies attach peptides to surfaces while preserving their binding capabilities.
- High-selectivity biomolecule isolation – Peptide-coated supports are used to enrich target molecules from complex mixtures.
- Controlled surface chemistry – Researchers adjust peptide density and orientation to fine-tune capture properties.
These technologies improve molecular capture workflows by leveraging peptide specificity and tunability to build functional surfaces for analytical and preparative research.