Overview
Analytical reference standards are critical for verifying instrument performance, calibrating assays, and ensuring reproducible measurements. Peptides are increasingly chosen as reference standards because their sequences can be defined precisely and their physical properties are well-characterized. High-purity peptide standards support quality control in chromatographic, spectrometric, and spectroscopic methods used across a wide range of research-only applications.
Peptide standards are typically designed to be stable, soluble, and analytically robust. They can be tailored to specific mass ranges, retention times, or detection modes, making them highly adaptable to different laboratory platforms.
Research Topics
- Standardized purity benchmarks – Peptides with carefully documented purity profiles serve as benchmarks for instrument performance and sample comparison.
- MS calibration peptides – Well-defined mass-to-charge signatures help verify mass accuracy and resolution in mass spectrometry workflows.
- Retention-time reference peptides – In HPLC and related systems, reference peaks facilitate retention-time alignment across runs and instruments.
- Quantitative assay standards – Known concentrations of peptide standards enable accurate calibration curves for quantitative analyses.
Through continued research and refinement, peptide-based reference standards strengthen analytical accuracy and reproducibility without extending beyond their intended use in laboratory and method-development contexts.